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目的:探索感咳双清胶囊在慢性咽炎的全程干预治疗中的作用。方法:采用随机对照的研究方法。共入组100例临床诊断为慢性单纯性咽炎的患者,患者随机接受加与不加感咳双清的全程干预治疗,对有效性,急性发作次数、发作持续时间、合并用药等指标进行了长达48周的随访观察。结果:在治疗的第4、第8周,两组间各有效性指标均无显著差异;但在治疗第48周时,在临床治愈率和完全缓解率两个指标上,试验组(22.0%,42.0%)优于对照组(8.0%,22.0%)。治疗组急性发作次数,平均每次发作持续时间,每次发作需要使用抗菌素的机会,抗菌素需要使用的疗程均显著短于对照组。结论:感咳双清可以帮助慢性单纯性咽炎的患者提高临床治愈率,减少急性发作次数,缩短发作持续时间,减少急性发作时合并细菌感染的危险,减少需要使用抗菌素的机会,减少使用抗菌素的疗程。
Objective: To explore the role of “Ke Ke Shuang Qing Capsule” in the treatment of chronic pharyngitis. Methods: A randomized controlled study was used. A total of 100 patients with clinically diagnosed chronic simple pharyngitis were enrolled in the study. Patients were randomized to receive either complete or full treatment with or without cough and clear serum. The efficacy, number of exacerbations, duration of attack, Up to 48 weeks follow-up observation. Results: At the 48th week of treatment, there was no significant difference in the validity indexes between the two groups at the 4th and 8th week of treatment. On the two indexes of clinical cure rate and complete remission rate, the test group (22.0% , 42.0%) than the control group (8.0%, 22.0%). The number of acute attacks, the average duration of each attack, and the duration of each episode required the use of antibiotics, and the duration of antibiotic therapy was significantly shorter in the treatment group than in the control group. Conclusions: Qi Ke Shuangqing can help patients with chronic simple pharyngitis to improve clinical cure rate, reduce the number of acute attacks, shorten the duration of attacks, reduce the risk of acute bacterial infections during acute attacks, reduce the need to use antibiotics and reduce the use of antibiotics Course of treatment.