在肿瘤的治疗中,紫杉烷代表了一类新的、独特的抗微管药物。它们的主要作用是通过促进极为稳定的微管聚集,从而导致癌细胞死亡并抑制组织的正常再生。值得注意的是该类药物对铂治疗无效的患者的疗效。紫杉醇的发展道路很不平坦,主要由于该药水溶性差,生产难度大及高敏感性等问题。这样,尽管其有很大的疗效潜力,但是还 In the treatment of tumors, taxanes represent a new class of unique anti-microtubule drugs. Their main role is to promote the death of cancer cells and inhibit the normal regeneration of tissues by promoting the accumulation of extremely stable microtubules. It is worth noting the efficacy of this class of drugs in patients who have failed platinum therapy. Paclitaxel’s development path is very uneven, mainly due to the poor solubility of the drug, production difficulties and high sensitivity and other issues. In this way, despite its great therapeutic potential, it still has