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目的：探讨抗心磷脂抗体（ＡＣＬＡ）与复发性脑梗塞（ＲＣＩ）的关系。方法：采用ＥＬＩＳＡ方法检测了３７例ＲＣＩ患者和６８例首发性脑梗塞（ＦＣＩ）患者的血清ＡＣＬＡ，并与对照组５０例进行比较。结果：ＲＣＩ、ＦＣＩ及对照组的ＡＣＬＡ阳性率分别为６４．８６％、３２．３５％及１６％，ＲＣＩ及ＦＣＩ组的ＡＣＬＡ阳性率与对照组ＡＣＬＡ阳性率比较差异均有统计学意义（Ｐ＜０．０１、Ｐ＜０．０５）；同时ＲＣＩ组ＡＣＬＡ阳性率也明显高于ＦＣＩ组ＡＣＬＡ阳性率（Ｐ＜０．０１）。阳性病例ＡＣＬＡ分型中，ＲＣＩ及ＦＣＩ组中ＩｇＧ型ＡＣＬＡ阳性率与对照组ＩｇＧ型ＡＣＬＡ阳性率比较差异有统计学意义（Ｐ＜０．０１），ＲＣＩ组中ＩｇＭ型ＡＣＬＡ阳性率也明显高于对照组ＩｇＭ型ＡＣＬＡ阳性率（Ｐ＜０．０５）。ＲＣＩ组中男女人数比值为３．６３。结论：ＡＣＬＡ可能为ＲＣＩ发生的危险因素。
Objective: To investigate the relationship between anticardiolipin antibody (ACLA) and recurrent cerebral infarction (RCI). Methods: The serum levels of ACLA in 37 patients with RCI and 68 patients with primary cerebral infarction (FCI) were measured by ELISA and compared with 50 patients in control group. Results: The positive rates of ACLA in RCI, FCI and control group were 64.86%, 32.35% and 16%, respectively. The positive rates of ACLA in RCI and FCI groups were significantly different from those in control group (P <0.01, P <0.05). Meanwhile, the positive rate of ACLA in RCI group was also significantly higher than that in FCI group (P <0.01). In the positive cases of ACLA, the positive rate of IgG-type ACLA in RCI and FCI group was significantly higher than that in control group (P <0.01), and the positive rate of IgM-type ACLA in RCI group was also significantly higher The positive rate of IgM ACLA in control group (P <0.05). The ratio of men to women in the RCI group was 3.63. Conclusion: ACLA may be a risk factor for RCI.