目的探讨单鼻孔蝶窦入路垂体腺瘤切除术的外科技术。方法总结2004年1月至2007年12月22例经单鼻孔蝶窦入路垂体腺瘤手术患者的临床资料,其中微腺瘤2例,大腺瘤8例,巨大腺瘤12例。结果肿瘤全切除16例,大部分切除3例,部分切除3例。结论经单鼻孔蝶窦入路垂体腺瘤切除术是一种安全、有效、微创的外科技术。 Objective To investigate the surgical technique of single nostril sparing sinus pituitary adenoma resection. Methods From January 2004 to December 2007, 22 patients with pituitary adenomas underwent single nostril sphenoid sinus surgery were enrolled in this study. Among them, 2 were microadenomas, 8 were large adenomas and 12 were giant adenomas. Results Total resection in 16 cases, most of the resection in 3 cases, partial resection in 3 cases. Conclusion Single nostril sphenoid sinus pituitary adenoma resection is a safe, effective and minimally invasive surgical technique.