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目的 观察低浓度克矽平大容量全肺灌洗术治疗煤工尘肺的疗效。方法 42名男性煤工尘肺患者用分层配对方法确定治疗组和对照组。治疗组 2 1名患者接受大容量肺灌洗术治疗。两组随访时进行问诊调查、肺功能和胸部X线摄片检查。结果 肺灌洗治疗能洗出一定量的粉尘 ,其中快型尘肺平均每例的粉尘洗出量为 981.2mg,明显多于慢型尘肺 (386 .2mg) ,差异有显著性 (P <0 .0 5 ) ;治疗组疗前、疗后 2年、疗后 6年的FEV1.0 值分别为 3.35、3.2 9和 2 .75L ,对照组为 2 .95、2 .73和 2 .41L ,均随年龄增加有下降趋势 ,但两组的差异无显著性 (P >0 .0 5 )。治疗组治疗后 6年胸片的稳定率和进展 (进展及明显进展 )率分别为 42 .1%和 5 7.9% ,对照组分别为 5 7.9%和 42 .1% ,两组的差异无显著性 (P >0 .0 5 )。结论 大容量全肺灌洗术能洗出肺内一定量的粉尘 ,但对肺功能改善和阻止病变进展未见明显疗效
Objective To observe the curative effect of low concentration Kexiao Ping large-capacity whole lung lavage in the treatment of coal worker’s pneumoconiosis. Methods Forty-two male coal workers with pneumoconiosis were divided into treatment group and control group by stratified pairing method. Twenty-one patients in the treatment group received massive lung lavage. Two groups were interviewed for investigation, lung function and chest X-ray examination. Results Pulmonary lavage treatment can wash out a certain amount of dust, of which an average of 981.2mg per case of fast pneumoconiosis was significantly more than that of chronic pneumoconiosis (386.2mg), the difference was significant (P <0. The values of FEV1.0 before treatment, 2 years after treatment and 6 years after treatment in the treatment group were 3.35, 3.29 and 2.75 L, respectively, and those in the control group were 2.95, 2.73 and 2.41 L With age, there is a downward trend, but there was no significant difference between the two groups (P> 0.05). The stability rate and progress (progress and significant progress) of the chest radiograph in the treatment group at 6 years after treatment were 42.1% and 5 7.9%, respectively, while the control group was 5 7.9% and 42.1% respectively, with no significant difference between the two groups Sex (P> 0.05). Conclusion Large-capacity whole-lung lavage can wash out a certain amount of dust in the lungs, but there is no obvious effect on improving pulmonary function and preventing the progression of the disease