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目的分析呼吸道感染患者黏液型铜绿假单胞菌(PAE)的年龄分布及药敏结果 ,为临床抗感染治疗选药提供依据。方法收集40例(40株)住院患者合格呼吸道样本分离出的黏液型PAE进行纸片扩散法(K-B法)48 h读取药敏试验,另查LIS系统并进行统计。结果 40例呼吸道感染产黏液型PAE患者中≤49岁2例(5.0%),50~59岁4例(10.0%),60~69岁8例(20.0%),70~79岁11例(27.5%),≥80岁15例(37.5%)。≥60岁老年患者共有34例(85.0%)。且易复发感染;分离出黏液型PAE对多粘菌素、碳青霉烯类(亚胺培南、美罗培南)、哌拉西林/他唑巴坦、氨基糖苷类(庆大霉素、阿米卡星)、头孢类(头孢他啶、头孢吡肟)和哌拉西林抗菌药敏感性较高,均>80%。结论黏液型PAE是老年人呼吸道感染的重要影响因素,应加强对该菌的分离与鉴定,及时告知临床医生,为早期治疗控制感染提供依据,减少感染的复发。
Objective To analyze the age distribution and drug susceptibility of mucoid Pseudomonas aeruginosa (PAE) in patients with respiratory tract infection and provide the basis for clinical anti-infection treatment and drug selection. Methods Mucolytic PAE isolated from 40 patients (40 isolates) from hospitalized patients were collected for mucosal PAE for 48 h. The K-B method was used to read drug susceptibility test. The LIS system was also investigated and statistically analyzed. Results Two cases (5.0%) of 49 patients with mucinous PAE were found in 40 cases of respiratory tract infection, 4 cases (10.0%) were in 50-59 years old, 8 cases (20.0%) were in 60-69 years old and 11 cases were in 70-79 years old 27.5%), ≥80 years in 15 cases (37.5%). A total of 34 patients (85.0%) were older than 60 years old. And easy to relapse infection; mucolytic PAE isolated polymyxin, carbapenems (imipenem, meropenem), piperacillin / tazobactam, aminoglycosides (gentamicin, A Mika Star), cephalosporins (ceftazidime, cefepime) and piperacillin antibacterials higher sensitivity, were> 80%. Conclusions Mucoid PAE is an important influencing factor of respiratory tract infection in the elderly. The isolation and identification of this bacterium should be strengthened. Clinicians should be informed timely to provide basis for early treatment and control of infection and reduce the recurrence of infection.