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用定群血清流行病学方法观察HFRS疫苗效果考核现场对照组人群隐性感染情况。采用IFAT检则血清中HFRSIgG抗体,分析不同性别和年龄人群的隐性感染及感染后抗体水平变化情况。结果,HFRS年感染率为229%,在不同性别和年龄组中未见显著差异;32名隐性感染者HFRS抗体转阴率4688%,HFRS抗体上升率达2500%,在不同HFRS抗体滴度、性别和年龄组中未见显著差异。此观察结果为疫苗现场效果评价提供一些背景资料。
Serological epidemiological methods were used to observe the effect of HFRS vaccination in the field control group. IFRS test serum HFRSIgG antibody analysis of different gender and age groups, latent infection and antibody levels after infection changes. As a result, the annual infection rate of HFRS was 229%, and there was no significant difference among different sexes and age groups. The negative rate of HFRS antibody in 32 latent infections was 4688%, and the rate of HFRS antibody increased was 2500% There were no significant differences in titers, sexes and age groups for different HFRS antibodies. This observation provides some background information for the evaluation of the efficacy of vaccines.