地高辛 Jaeschke等(Am J Med 1990;88: 279-286)系统评述和分析了1966-1988年发表的有关地高辛对窦性节律充血性心力衰竭患者的疗效。结果表明,12％(95％可信限为3-20％)的患者临床上取得显著效益,作者认为,对于心肌收缩功能不全和中至重度的心力衰竭患者,地高辛才有可能取得最大效果。他们建议,对于病情不很严重和不大可能得到效益的患者,谨慎撤除地高辛是一项安全和明智的措施。 Digoxin’s Jaeschke et al. (Am J Med 1990; 88: 279-286) systematically reviewed and analyzed the efficacy of digoxin in patients with sinus rhythm congestive heart failure published 1966-1988. The results showed that 12% (95% confidence limit of 3-20%) patients clinically significant benefits, the authors believe that for patients with myocardial systolic dysfunction and moderate to severe heart failure, digoxin was the largest possible effect. They suggest that a cautious withdrawal of digoxin is a safe and sane measure for patients who are less likely to benefit and less likely to benefit.