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目的：探讨建立薄荷药材的提取和含量测定方法。方法以薄荷脑为指标成分，采用DM-FFAP弹性石英毛细管柱，初始柱温为120℃，以2℃/min升温至140℃，然后以15℃/min升温至220℃，保持5 min。比较索氏提取、加热回流、超声提取法的差异，并优选最佳提取方法。结果最佳提取工艺院加10倍量无水乙醇溶液85℃回流提取1 h。薄荷脑在34.034~343.04μg/ml浓度范围内线性关系良好，平均回收率为99.00%，RSD=1.87%(n=6)。结论本文所建立的提取和含量测定方法快速简便、结果可靠，可为薄荷药材质量控制提供科学依据。“,”Objective To explore the methods for extraction and content determination on Mentha haplocalyx Briq. Methods Menthol was as the index components.DM-FFAP chromatographic column was applied,with initial tempera-ture set at 120℃,then heated up to 140℃ at the speed of 2℃/min,then heated up to 220℃ at the speed of 15℃/min, then maintained the temperature at 220℃for 5 minutes.The optimal extraction method was selected based on compari-son of Soxhlet extraction,heat reflux extraction and ultrasonic extraction. Results The study identified the optimal ex-traction process: adding 10 times amount of anhydrous ethanol solution then heat reflux extraction under 85℃ water bath for 1 hour.Menthol had good linear relation at the concentration of 34.034-343.04 μg/ml,with average recovery rate of 99.00%,RSD=1.87% (n=6). Conclusion The extraction and content determination methods developed in the study are quick,simply,conveninent and reliable,providing scientific basis for quality control of Mentha haplocalyx Briq.