全国肿瘤防治研究办公室恶性肿瘤发病登记资料显示:女性乳腺癌发病率占当地女性恶性肿瘤第一或第二位,病死率为女性恶性肿瘤第四或第五位,且病死率正呈现逐年增高的趋势[1]。近几年,蛋白质组学技术已广泛应用于生物医学研究的各个领域,也逐步应用于乳腺癌的研究。1蛋白质组学概 National Cancer Research Office malignant tumor registration data show that: the incidence of female breast cancer accounted for the first female or local malignant tumors, the second or fifth death rate of female malignant tumors, and the mortality rate is increasing year by year Trend [1]. In recent years, proteomics technology has been widely used in various fields of biomedical research, but also gradually applied to breast cancer research. 1 proteomics outline