海马硬化症是部分性边缘叶癫痫最常见的病理学基础。双重病理学是指边缘叶癫痫患者海马内细胞减少同时伴有海马外病变。本文回顾分析了178例行颞叶切除术治疗的顽固性癫痫患者的资料。发现海马内细胞减少和海马外病变同时存在的双重病理学改变者54例(30.3％)。并将其海马内细胞减少的 Hippocampal sclerosis is the most common pathological basis of partial limbal leaf seizures. Dual pathology refers to the reduction of cells in the hippocampus in patients with limbic lobe epilepsy accompanied by extrahepatic lesions. This article retrospectively reviewed 178 patients with refractory epilepsy treated with temporal lobe resection. Fifty-four patients (30.3%) were found to have double pathological changes in both hippocampus and extra-hippocampal lesions. And reduce their hippocampal cells