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目的探讨肝硬化腹水并低钠血症的发病因素及治疗方法。方法将本院近两年收治的45例肝硬化腹水并低钠血症患者作为观察组,选择同期收治的45例肝硬化腹水未出现低钠血症患者作为参考组,比较两组患者临床资料、临床治疗效果。结果单因素分析显示患者呕吐、恶心、过度利尿、排腹水、钠摄入严格等均是导致肝硬化腹水并低钠血症的重要因素(P<0.05);观察组患者肝肾综合征、肝性脑病、顽固性腹水发生率明显高于参考组(P<0.05);两组患者治疗总有效率存在显著差异,比较差异有统计学意义(P<0.05)。结论针对低钠血症发生的因素给予针对性预防和处理,有助于改善预后,提高患者生存率。
Objective To investigate the pathogenesis of ascites and hyponatremia in cirrhosis and its treatment. Methods Forty-five patients with cirrhosis and hyponatremia treated in our hospital in recent two years were selected as the observation group. 45 patients with hyponatremia who did not appear ascites in the same period were selected as the reference group. The clinical data of the two groups were compared , Clinical treatment effect. Results Univariate analysis showed that patients with vomiting, nausea, excessive diuresis, ascites, strict sodium intake and so on are the leading factors of cirrhosis with hyponatremia and hyponatremia (P <0.05); observation group patients with hepatorenal syndrome, liver The incidence of encephalopathy and refractory ascites was significantly higher than that of the reference group (P <0.05). There was significant difference in the total effective rate between the two groups (P <0.05). Conclusions The targeted prevention and treatment of hyponatremia may be helpful to improve the prognosis and improve the survival rate of patients.