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目的探讨可溶性细胞间粘附分子1(Solubleintercellular adhesion molecule,sICAM-1)与胃癌侵袭转移的关系.方法用双抗体夹心法测定53例胃癌患者,20例胃癌前期病变患者及20例正常人血清中sICAM-1水平,并观察胃癌根治术前后患者血清sICAM-1水平的变化.结果胃癌患者血清sICAM-1水平为541.5 ng/ml,明显高于胃癌前期病变患者(306.8 ng/ml)及正常人(294.3 ng/ml)(P<0.01);I期患者血清sICAM-1水平明显低于Ⅲ期与Ⅳ