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国产枢丹（Zudan）属强效5－羟色胺3（5－HT3）受体拮抗剂，其化学结构、止吐作用机制与进口的枢复宁（Ondansetron）相同。为观察其临床止吐效果，我们于1996年8月～1999年10月对35例急性白血病化疗患者使用枢丹预防呕吐，并与枢复宁进行比较，观察两药在相等剂量下的疗效和毒
Domestic Zudan is a potent serotonin 3 (5-HT3) receptor antagonist and its chemical structure and antiemetic mechanism are the same as those of imported Ondansetron. To observe its clinical antiemetic effect, we used 35 patients with acute leukemia chemotherapy to prevent vomiting from August 1996 to October 1999. We compared the efficacy of the two drugs at equal doses with shufu ning. poison