急性异烟肼中毒在临床上并不少见,但急性异烟肼中毒致心跳呼吸停止并抢救成功者,国内文献尚未见报道。现将我院急诊科遇到的一例并结合文献复习报道如下。1 临床资料及复苏过程 患者女,38岁,因一次自服异烟肼20g后呕吐、抽搐、昏迷一小时,于1990年5月2日上午急诊入院。既往有肺结核病史,近几年来经常咳嗽、吐血痰、气促。入院后体检:体温37.8℃,脉搏100次,呼吸10次,血压13.3/9.33kPa,深昏迷,瞳孔散大约6mm,对光反射消失,两肺满布湿罗音,心 Acute isoniazid poisoning is not uncommon in clinical practice, but acute isoniazid poisoning caused by heartbeat stopped and rescued successfully, the domestic literature has not been reported. Now our hospital emergency department encountered an example combined with the literature review reported below. 1 Clinical data and recovery process Female, 38 years old, due to a self-service isoniazid 20g vomiting, convulsions, coma one hour, on the morning of May 2, 1990 emergency admission. Past history of tuberculosis, often cough in recent years, spit blood phlegm, shortness of breath. Physical examination after admission: body temperature 37.8 ℃, pulse 100, breathing 10 times, blood pressure 13.3 / 9.33kPa, deep coma, mydriasis about 6mm, the light reflection disappeared, both lungs full of moist rales, heart