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5. Integrin-interacting protein Kindlin-2 induces mammary tumors in transgenic mice

Integrin-interacting protein Kindlin-2 induces mammary tumors in transgenic mice

来源 :中国科学:生命科学英文版 | 被引量 : 0次 | 上传用户：lomon521mutou

【摘 要】

：

Kindlin-2, an integrin-interacting protein, regulates breast cancer progression. However, currently, no animal model to study the role of Kindlin-2 in the carci

【作 者】

：

Bing Li Xiaochun Chi Jiagui So 

【机 构】

：

DepartmentofAnatomy,InstituteofCardiovascularResearch

【出 处】

：

中国科学:生命科学英文版

【发表日期】

：

2019年2期

【关键词】

：

Kindlin-2 breast cancer MOUSE MAMMARY GLAND growth MAMMARY TUMORIGENESIS TRANSGE 

【基金项目】

：

supported by grants from the Ministry of Science and Technology of China (2016YFC1302103, 2015CB553906, and 2013CB910501),the National Natural Science Foundation of China (81730071, 81230051, 81472734

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Kindlin-2, an integrin-interacting protein, regulates breast cancer progression. However, currently, no animal model to study the role of Kindlin-2 in the carcinogenesis of mammary gland is available. We established a Kindlin-2 transgenic mouse model usin

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