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用药物累积法测定丁公藤注射液的表观动力学参数。结果表明:丁公藤注射液在小鼠体内符合一房室开放式模型,测得K=0.033h-1,T1/2=20.961h,Cl=0.066kg/(kg.h)等参数,为临床用药提供参考依据。
Determination of Apparent Kinetic Parameters of Dinggongtan Injection by Drug Accumulation. The results showed that the injection of Ding Gong Teng in mice consistent with an open chamber model, measured K = 0.033h-1, T1 / 2 = 20.961h, Cl = 0.066kg / (kg.h) and other parameters for the clinical use of drugs Provide a reference basis.