由于临床实践需要，常将抗癌药联合施用于患者。时间药物学研究表明，不仅单个抗癌药具有明显的节律性，而且联合用药也具昼夜节律性。目前，依时间节律制定抗癌药用药方案已在肿瘤模型动物取得了较好效果，并在临床上有了尝试性的应用，从而开始了实验治疗学的研究。本文拟对 Due to clinical practice, anticancer drugs are often administered to patients. Time-based pharmacological studies have shown that not only a single anticancer drug has a pronounced rhythm, but also that the combination drug has a circadian rhythm. At present, formulating anti-cancer drug regimens based on time rhythm has achieved good results in animal models of tumors, and has been applied experimentally in clinical practice, thus starting the study of experimental therapeutics. This article intends to