Occurrence of lymphoma in non-gonadal organ during pregnancy: a report on four cases and literature

来源 :Cancer Biology & Medicine | 被引量 : 0次 | 上传用户:g19801218
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Lymphoma rarely occurs during pregnancy, making this condition difficult to define. Lymphomas that occur in reproductive organs during pregnancy exhibit unique clinical characteristics. Among the limited cases, non-Hodgkin’s lymphoma(NHL) shows a considerably higher incidence rate than Hodgkin’s lymphoma(HL); NHL also displays clinical characteristics, such as high aggressiveness, advanced stage, and poor outcome. This study reports on four cases of lymphomas in non-gonadal organs(HL,n=2; NHL, n=2) during pregnancy. The tumors rapidly progressed in all patients during pregnancy but remitted at the end of pregnancy and/or therapy. The two HL cases were nodular sclerosis classical HL and treated with chemotherapy after terminating the pregnancy. One of the NHL cases was primary cutaneous follicular center lymphoma, a B cell-derived indolent lymphoma.The patient was followed up without any therapy after terminating her pregnancy. The other case was a follicular lymphoma grade3 B, which was treated with chemotherapy after delivery. We also conducted a literature review of 165 lymphoma cases occurring during pregnancy reported from 1976 to 2013 to reveal the correlation between pregnancy and lymphoma progression.Immunohistochemistry studies were performed to determine the expression of estrogen/progesterone receptors(ER/PR), and ER was weakly positive and sporadic. We concluded that lymphomas occurring during pregnancy should be managed with a prompt and reasonable treatment. High estrogen level in maternal body may affect lymphoma progression. Lymphoma rarely occurs during pregnancy, making this condition difficult to define. Lymphhomas that occurs in pregnancy, make this condition difficult to define. Lymphoma rarely occurred during pregnancy, making this condition difficult to define. Lymphoma rarely occurring during pregnancy, making this condition difficult to define. ; NHL also displays clinical characteristics, such as high aggressiveness, advanced stages, and poor outcomes. This study reports on four cases of lymphomas in non-gonadal organs (HL, n = 2; NHL, n = 2) during pregnancy. rapidly progressed in all patients during pregnancy but remitted at the end of pregnancy and / or therapy. The two HL cases were nodular sclerosis classical HL and treated with chemotherapy after terminating the pregnancy. One of the NHL cases was primary cutaneous follicular center lymphoma, a B cell-derived indolent lymphoma.The patient was followed up without any therapy after terminating her pregnancy. The other case was a follicular lymphoma grade 3 B, which wa We also conducted a literature review of 165 lymphoma cases occurring during pregnancy reported from 1976 to 2013 to reveal the correlation between pregnancy and lymphoma progression. Immunohistochemistry studies were performed to determine the expression of estrogen / progesterone receptors (ER / PR), and ER was weakly positive and sporadic. We noted that lymphomas occurring during pregnancy should be managed with a prompt and reasonable treatment. High estrogen level in maternal body may affect lymphoma progression.
其他文献
我站现有15人,其中业务人员十三名,绝大多数是青年。他们中有些是顶替参加工作的,文化程度低,专业知识差。在这种情况下,怎样提高质量,做好工作,是我站多年来认真研究和实践
阅读能力是学习的基础,教师需要利用好这一平台丰富内容,帮助幼儿更快、更好掌握阅读的技巧与方法,开展多元化的活动,让幼儿在一系列的阅读活动中可以养成良好的阅读习惯并积
民间游戏作为中华民族传统文化的一部分,承载着中华文化的传承,对于幼儿的身心发展有重要的作用.本文将民间游戏引入A园并进行实践探索,并发现引入过程存在幼儿园管理者过于
国子学是魏晋南北朝时期的最高学府和教育机构,为士族子弟所设,始建于西晋武帝时期,在东晋南朝逐步得到发展完善,并直接影响着以后隋唐各代的教育制度。国子学以教授儒家经典
AIM To identify the frequency, clinicopathological risk factors, and prognostic significance of lymphovascular invasion(LVI) in endoscopically resected small re
对不同核质基因型杂交种的产量性状进行了分析。结果表明,不同核质遗传背景杂种的产量差异主要是由核基因型不同所致;不育胞质对杂交种的产量性状具有一定的正效应,C和E型不育胞质
Background: It remains controversial whether palliative primary tumor resection(PPTR) can provide survival benefits to the patients with metastatic colorectal c
摘 要:在幼儿教育教学的过程中,玩教具展现出了巨大的作用和价值。教师在实际开展幼儿教学的过程中,可以通过玩教具为幼儿提供丰富多样的教学模式,让幼儿的语言表达能力、动手操作能力和想象力随之提升。通常情况下,在教学中合理运用玩教具就会引导幼儿朝着良好的方向发展,让幼儿在玩乐中感受到学习的魅力和价值。同时,教师在实际开展教学的过程中应该关注多个层面,积极认真落实幼儿教育教学。本文重点阐释了玩教具在幼儿教
智库产业发展的机制特点(一)智库产业的定义早在1953年,美国学者①就已提出了第四产业和第五产业(Quaternary and Quinary Sector)的概念,它们可以被看作是第三产业的延伸。
《易经》是一部博大精深、融会贯通的巨著。本文作者阐述了《易经》中的和谐统一理念、“中庸之道”思想以及《易经》的持经达变观点,并将“此三”称之为“易经”梭面所折射