近年国外胰腺癌发病率渐高,目前大多数西方国家的发病率为9～10/10万/年,尤以75岁以上者为甚,可高达100/10万/年。多数息者在确诊后6个月内死亡,这是由于首发症状很不明确,特异性不强;胰腺又难于检查;病程早期即可转移扩散。与慢性胰腺炎的鉴别尤使临床医师棘手,故往往贻误诊断。本文主要介绍近二年胰腺导管癌诊断方面的进展,以资借鉴。一、症状和体征的分析疼痛是50～80%患者的首发症状,病程中出现疼痛可高达90%。胰头癌疼痛局限于上腹部和/或右上腹,且常在进食后加重;而 In recent years, the incidence of pancreatic cancer in foreign countries is gradually increasing. The current incidence rate in most Western countries is 9 to 10/10 million per year, especially among those over 75, and it can be as high as 100 per 100 000 per year. Most of the people who died died within 6 months of diagnosis. This is due to the fact that the first symptoms are unclear and the specificity is not strong; the pancreas is difficult to check; and the disease can spread during the early stages of the disease. The identification of chronic pancreatitis is particularly tricky for clinicians, so it often delays diagnosis. This article mainly introduces the progress in the diagnosis of pancreatic ductal carcinoma in the last two years. First, the analysis of symptoms and signs of pain is 50 ~ 80% of patients with the first symptoms, pain during the course of up to 90%. Pancreatic head cancer pain is limited to the upper abdomen and/or right upper abdomen, and often aggravates after eating;