肝豆状核变性(HLD),因临床表现多样化,早期诊断不易。现将我院3例报告如下。例1,女,7岁,1984年因说话不清,进食流涎,双下肢跛行,发热、牙齦出血入院。患儿于1981～1982年,以黄疸性肝炎。先后3次在传染病院治疗,治疗后肝损害加重,伴腹水,继发多系统损害(全血细胞减少,心肌和肾损害),考虑“恶网”和“胶原性疾病”,赴外地就诊,排除了上述疾病,仍按肝病治疗。查体:T33℃,齿龈出血, Hepatolenticular degeneration (HLD), due to the diversity of clinical manifestations, early diagnosis is not easy. Now my hospital 3 cases reported as follows. Example 1, female, 7 years old, 1984 due to vomiting, eating salivation, both lower limbs lameness, fever, bleeding gums admission. Children from 1981 to 1982, with jaundice hepatitis. He has been treated in an infectious disease hospital three times. After treatment, the liver damage is aggravated, with ascites secondary to multiple system damage (pancytopenia, myocardial and renal damage), and the “evil net” and “collagen diseases” are considered for treatment and exclusion The above diseases are still liver disease treatment. Physical examination: T33 ℃, bleeding gums,