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目的探讨自体口唇粘膜联合新鲜羊膜、结角膜缘移植治疗严重睑球粘连的临床治疗效果。方法对28例28眼有严重睑球粘连及假性胬肉的患者进行睑球粘连松解后,应用自体唇粘膜移植进行睑结膜和穹窿结膜修复,羊膜和自体结角膜缘组织瓣移植重建球结膜和角膜表面,观察其临床效果。结果术后观察6-12个月,15例患眼疗效为优,眼睑球粘连均得到明显改善,眼表基本上恢复正常。12例疗效为良,睑球粘连部分复发,但较术前有所改善。1例因上下睑球全粘连结膜囊闭锁愈后效果较差。结论自体唇粘膜联合新鲜羊膜、结角膜缘移植重建眼表是治疗较严重睑球粘连的有效实用理想的方法。
Objective To investigate the clinical effect of autologous oral mucosa combined with fresh amniotic membrane and keratoconus transplantation for the treatment of severe symblepharon. Methods Twenty-eight eyes of 28 patients with severe symblepharon and pseudo-pterygium were treated with symblepharon release and autologous lip mucosa transplantation for palpebral conjunctiva and fornix conjunctival repair. The amniotic membrane and limbal autograft flap reconstruction Conjunctiva and corneal surface, observe its clinical effect. Results The postoperative observation of 6-12 months, 15 cases of eye efficacy is excellent, the eyelid ball adhesion were significantly improved, the eye table basically returned to normal. 12 cases of good efficacy, symblepharon recurrence, but improved compared with preoperative. 1 case due to the whole upper and lower eyelid conjunctiva closure of the capsule after the poor results. Conclusions Autologous lip mucosa combined with fresh amnion and conjunctival limbal remodeling is an effective and practical method for the treatment of severe symblepharon.