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目的:探讨颅内上皮样血管内皮瘤(EHE)的临床、病理、影像学特征及治疗方法。方法:通过苏木精-伊红染色、免疫组化法观察1例颅内EHE病例,并结合文献报道资料较为完整的26例颅内EHE病例进行分析探讨。结果:颅内EHE诊断有赖于病理确诊,其生物学行为介于良、恶性之间的中间型或未定型,呈弥漫浸润生长但不转移。结论:颅内EHE临床罕见,极易误诊,组织形态需与转移癌、黏液性软骨肉瘤、脊索样脑膜瘤及转移性心房黏液瘤等鉴别。
Objective: To investigate the clinical, pathological, imaging features and treatment of intracranial epithelial hemangioendothelioma (EHE). Methods: One case of intracerebral EHE was observed by hematoxylin - eosin staining and immunohistochemistry, and 26 cases of intracranial EHE with complete literature reported were analyzed. Results: The diagnosis of intracranial EHE depends on the pathological diagnosis. The biological behavior of EHE is intermediate or undetermined between benign and malignant. It is diffusely infiltrated but not metastasized. Conclusion: Intracranial EHE is clinically rare and easily misdiagnosed. The morphology of the intracerebral EHE should be differentiated from metastatic carcinoma, myxomatous chondrosarcoma, chordate-like meningioma and metastatic atrial myxoma.