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磷酸咯啶(研制号6701)是上海第十四制药厂研制的新抗疟药,化学名为3-氯-7-甲氧基-9-{3′,5′-双-[(N-吡咯烷基)甲基]-4′-羟苯胺基}吖啶的三磷酸盐。临床用于疟疾抑制性治疗,具有控制症状快,副作用较小等优点,但仍需与伯喹(伯氨喹啉)合用,以杀灭恶性疟原虫配子体和间日疟抗复发治疗。已知阿的平(Quinacrine)与扑疟喹啉(Pamaquine)合用
Phosphoric acid pyrrolidine (No. 6701) is a new antimalarial drug developed by the 14th Shanghai Pharmaceutical Factory and has the chemical name of 3-chloro-7-methoxy-9- {3 ’, 5’-bis- [ Pyrrolidinyl) methyl] -4’-hydroxyanilino} acridine. Clinically used for malaria suppressive therapy, with the advantages of rapid control of symptoms, fewer side effects, but still need to be combined with primaquine (primaquine quinoline) to kill Plasmodium falciparum gametophyte and anti-relapsing treatment of vivax malaria. Quinacrine is known to be used in combination with Pamaquine