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目的探讨脑出血患者血液流变学改变的影响因素,以指导临床采取及时、正确的干预措施,促进神经功能的恢复。方法收集神经内科住院的脑出血病例157例,均经头颅CT确诊,测定其血液流变学指标,并对可能影响脑出血患者血液流变学指标的因素(高血压病史、糖尿病史、高脂血症、冠心病史、出血量、出血部位、血肿是否破入脑室、入院时血压、神经功能缺损评分、入院后进食情况、脱水剂、体温和预后)进行单因素分析,把有意义的变量引入两分类反应的非条件Logistic回归分析。结果采用两分类反应变量的非条件Logistic回归分析,最后进入Logistic回归模型的影响高切血粘度的因素有6个,分别是高血压病史、糖尿病史、冠心病史、出血量、入院后进食情况和脱水剂。结论引起ICH患者血粘度增高的主要因素有高血压病史、糖尿病史、冠心病史、出血量、脱水剂及入院后进食情况。
Objective To explore the influencing factors of hemorheological changes in patients with intracerebral hemorrhage so as to guide the clinic to take timely and correct interventions and promote the recovery of neurological function. Methods A total of 157 cases of intracerebral hemorrhage in neurology department were collected, all of them were confirmed by skull CT. The indexes of hemorheology were determined. The indexes of hemorheology, such as history of hypertension, history of diabetes mellitus, Coronary heart disease, blood loss, bleeding site, hematoma was broken into the ventricle, admission blood pressure, neurological deficit score, admission after eating, dehydration agent, body temperature and prognosis) univariate analysis, the meaningful variables Non-conditional logistic regression analysis was introduced to introduce the two classification reactions. Results The non-conditional logistic regression analysis of two-category response variables, and finally into the Logistic regression model of factors affecting the high blood viscosity, there are 6 factors: history of hypertension, history of diabetes, history of coronary heart disease, blood loss, food intake after admission And dehydrating agent. Conclusions The main factors leading to the increase of blood viscosity in patients with ICH are history of hypertension, history of diabetes mellitus, history of coronary heart disease, amount of bleeding, dehydrating agent and post-admission food intake.