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目的:调查分析武汉地区32家医院大环内酯类抗菌药物用药的现状及趋势。方法:以用药量、用药金额、限定日剂量(DDD)、用药频度(DDDs)、日均费用(DDC)等指标,分析其临床应用情况并预测未来趋势。结果:除克拉霉素和麦迪霉素外,大多数药物总用药量、用药金额、DDDs呈逐年下降趋势。前5位药物总用药金额分别占全年总用药金额的97.20%,97.38%,98.11%;前5位用药频繁的药物中,DDC在3.19～12.64元/日。结论:应继续加强抗菌药物的管理,促进大环内酯类抗菌药物合理应用。
Objective: To investigate the status and trends of macrolide antibiotics in 32 hospitals in Wuhan. Methods: The clinical application and the prediction of future trends were analyzed with the dosage, dosage, DDD, DDDs and DDC. Results: In addition to clarithromycin and midecamycin, the total amount of drugs, the amount of medication, DDDs showed a downward trend year by year. The total amount of medication of the first 5 drugs accounted for 97.20%, 97.38% and 98.11% respectively of the total amount of medication for the whole year. DDC was 3.19-12.64 yuan / day in the top 5 drugs with frequent medication. Conclusion: The administration of antimicrobial agents should be further strengthened and the rational use of macrolide antibiotics should be promoted.