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对放置串铜394（SCu394）宫内节育器（IUD）、TCu220cIUD后的恒河猴和人的子宫膜进行光镜和电镜观察。结果表明：SCu394IUD组子宫内膜主要病理变化是间质炎性反应，微血管扩张，血管内皮细胞变性，基底膜稀疏，红细胞漏出，子宫腔上皮缺损，微绒毛减少、断裂。以子宫异常出血者变性最明显。与TCu220cIUD比较，结果类似。
The uterine membrane of rhesus monkeys and human after TCu220cIUD was placed under light and electron microscopy on the IUD, SCu394 (SCu394) IUD. The results showed that the main pathological changes of endometrium in SCu394IUD group were interstitial inflammatory reaction, microvascular dilatation, degeneration of vascular endothelial cells, sparse basement membrane, leakage of erythrocytes, uterine cavity epithelial defects, reduction of microvilli and rupture. Uterine abnormal degeneration of the most obvious. Compared with TCu220cIUD, the results are similar.