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72例缺氧缺血性脑病新生儿随机分为丹参注射液治疗组和常规治疗组各36例,两组患儿在一般情况、孕产期情况和临床表现方面相似(P>0.05)。结果显示:在新生儿原始反射异常、惊厥、中枢性呼吸衰竭、超声影像学分度等方面丹参组都优于常规组(P<0.05),临床分度方面丹参组也比常规组明显减轻(P>0.05)。10例丹参组患儿检测了丹参注射液给药前和给药中脑血流的变化,证实丹参注射液能增加脑血流,降低脑血管阻力指数。我们认为丹参注射液能减轻新生儿缺氧缺血性脑损伤。
Thirty-two neonates with hypoxic-ischemic encephalopathy were randomly divided into two groups, 36 cases in each group. The two groups were similar in general condition, pregnancy stage and clinical manifestation (P> 0.05). The results showed that: Salvia miltiorrhiza group was superior to the conventional group (P <0.05) in the neonatal primary reflex abnormalities, convulsions, central respiratory failure, ultrasound imaging degree and so on, Salvia miltiorrhiza group was also significantly lower than the conventional group (P> 0.05). Ten cases of Salvia miltiorrhiza group were tested before and after administration of Salvia injection of blood flow changes in the brain, confirmed Salvia injection can increase cerebral blood flow, reduce cerebral vascular resistance index. We think Salvia Injection can reduce neonatal hypoxic-ischemic brain damage.