论文部分内容阅读
目的 :观察硝苯吡啶对早产的治疗作用及不良反应。方法 :对 6 2例早产孕妇随机分为两组 ,分别静脉滴注硫酸镁和口服硝苯吡啶 ,以硫酸镁为对照 ,观察钙离子通道拮抗剂硝苯吡啶对早产的治疗、不良反应及新生儿结局。结果 :口服硝苯吡啶后显效时间为 3.6 8± 1.82 hr,总累计时间为 4.13± 1.2 3天 ,延长孕周 1.6 1± 0 .89周 ,足月分娩率 5 6 .2 5 % ,与硫酸镁同样有效 :主要不良反应为一过性血压降低、恶心、头痛等 ,占 31.38% (10 / 32 )。结论 :硝苯吡啶对早产治疗有效 ,且无明显不良反应。
Objective: To observe the therapeutic effect and adverse reaction of nifedipine on premature labor. Methods: Sixty-two preterm pregnant women were randomly divided into two groups. Intravenous magnesium sulfate and oral nifedipine were respectively administered. Magnesium sulfate was used as a control to observe the effects of nifedipine, a calcium channel antagonist, on preterm delivery, adverse reactions and neonatal Children’s ending. Results: The effective time of oral administration of nifedipine was 3.6 8 ± 1.82 hr with a total cumulative time of 4.13 ± 1.2 days, 1.6 weeks ± 0.89 weeks of gestational weeks, full-term delivery rate of 56.25% and sulfuric acid Magnesium is also effective: The main adverse reactions were transient hypotension, nausea and headache, accounting for 31.38% (10 of 32). Conclusion: Nifedipine is effective in the treatment of premature labor without obvious adverse reactions.