子宫内膜异位症(内异症)是妇科的一种常见病,据报道存在于60%的痛经妇女及40%～50%有慢性盆腔痛和性交痛的妇女中,在行经腹妇科手术的患者中,5%～15%被发现有此病。近年来,内异症发病率逐年上升,一般认为,内异症的发病细胞在病理上呈良性形态学表现,而临床上呈“恶性”的生物学行为,患者呈持续加重的盆腔粘连、疼痛、不孕。目前,尽管对内异症进行了大量基础和临床研究,但其发病机制仍未完全阐明。大量证据表明,免疫学因素在内异症的发病机制中起了重要的作用,其中巨噬细胞与内异症的关系备受关注,巨噬细胞及其分泌的细胞因子参与内异症的发生和发展。本研究应用免疫组化与蛋白印迹法检 Endometriosis (endometriosis) is a common gynecological disease, reportedly present in 60% of dysmenorrheal women and 40% to 50% of women with chronic pelvic pain and painful sexual intercourse, undergoing abdominal gynecological surgery Of patients, 5% to 15% were found to have this disease. In recent years, the incidence of endometriosis increased year by year, it is generally believed that the pathogenesis of endometriosis cells showed benign morphological features, and clinically “malignant” biological behavior, the patient was continuously increased pelvic adhesions , Pain, infertility At present, although a large number of basic and clinical studies on endometriosis, its pathogenesis has not yet been fully elucidated. A lot of evidence shows that immunological factors play an important role in the pathogenesis of endometriosis, macrophages and endometriosis concern, macrophages and their secretion of cytokines involved in the occurrence of endometriosis And development. In this study, immunohistochemistry and Western blotting were used