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人类免疫缺陷病毒(HIV)膜糖蛋白gp120在许多HIV感染的细胞表面均有表达,它可与正常细胞表面分子CD4结合。重组CD4衍生物(γCD4)是一种可溶性可与gp120结合的蛋白,此结合具有高度亲和性。它可作为向HIV感染细胞运送细胞毒
The human immunodeficiency virus (HIV) membrane glycoprotein gp120 is expressed on the surface of many HIV-infected cells and binds to the normal cell surface molecule CD4. Recombinant CD4 derivative (γCD4) is a soluble protein that binds to gp120, which binds with high affinity. It acts as a cytotoxic agent to HIV-infected cells