在近来的文献中,有几篇关于抗偏头痛药物舒马曲坦(sumatriptan)引起心脏不良反应的报道.为了评估本品不良反应的发生频率和特征,在本品于荷兰注册一年后进行了上市后研究.方法 由于荷兰86%的开业医师的大力帮助,于1992年7月对1727名服用舒马曲坦的病人进行了随访.1992年12月,通过普通医师把包括舒马曲坦的作用、不良反应及其他合用药物的调查表送给这些病人.在研究期中,有7例失访.在余下的1720例中,有1202人寄回了调查表(占70%),其中1187 In recent literature, there have been several reports of adverse cardiac effects caused by sumatriptan, an antimigraine drug. To assess the frequency and characteristics of adverse reactions in this product, the product was registered one year after registration in the Netherlands Post-marketing study.Methods A total of 1727 patients taking sumatriptan were followed up in July 1992 with the strong help of 86% of the practicing physicians in the Netherlands.In July 1992, , Adverse reactions and other co-medication questionnaires were sent to these patients during the study period, and in the study period, 7 were lost to follow-up questionnaires.Of the remaining 1720 cases, 1202 were returned to the questionnaire (70%), of which 1187