目的了解2012-2014年惠州市麻疹的流行特征,为促进免疫规划工作提供科学依据。方法运用描述性流行病学方法,对麻疹病例资料进行分析,同时对实验室检测结果进行分析。结果 2012-2014年惠州市共报告麻疹确诊病例1 412例,2013-2014年发病率比2012年显著上升。在7个区县中,D县发病率最高,为15.53/10万;病例主要集中在0~4岁年龄组,占病例总数的72.52%;散居儿童共有1 040例,占病例总数73.56%。8月龄~14岁麻疹病例中,无含麻疹类疫苗免疫史及免疫史不详占88.15%;分离出毒株15株,经省级实验室检测均属于H1基因型中的H1a基因亚型。结论惠州市麻疹疫情上升明显,消除麻疹工作任务艰巨,今后应进一步加强适龄儿童麻疹常规免疫,对漏种儿童和外来务工人员开展查漏补种,努力减少和消除免疫空白人群,控制疫情。 Objective To understand the epidemiological characteristics of measles in Huizhou from 2012 to 2014 and provide a scientific basis for promoting immunization planning. Methods Descriptive epidemiological methods were used to analyze the case data of measles and analyze the laboratory test results. Results A total of 1 412 measles cases were reported in Huizhou from 2012 to 2014. The incidence of measles cases in 2013-2014 increased significantly from 2012 to 2014. Among 7 districts and counties, the highest incidence was in D county, which was 15.53 / 100000; the cases mainly concentrated in the age group of 0-4 years old, accounting for 72.52% of the total number of cases; there were 1040 scattered children, accounting for 73.56% of the total cases. Among the measles cases aged from 8 months to 14 years, the immunization history with no measles vaccine and the history of immunization were 88.15% unknown. Fifteen isolates were isolated from the isolates. The provincial laboratory tests belonged to the H1 subtype of H1 genotype. Conclusion The epidemic situation of measles increased obviously in Huizhou City, and the task of eliminating measles was arduous. In the future, we should further strengthen routine immunization against measles in children of school age, carry out leak detection and replantation of children and migrant workers, and strive to reduce and eliminate immunized blank population and control the epidemic.