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目的探讨妊娠急性脂肪肝的诊断和治疗效果。方法回顾性分析我院2例妊娠急性脂肪肝患者的临床表现、实验室检查、妊娠结局并结合近年来文献报道进行总结。结果患者均以孕晚期纳差、腹胀、浮肿、黄疸、DIC为主要表现。超声呈“亮肝”表现。CT显示肝实质密度衰减。结论妊娠急性脂肪肝多根据临床表现和实验室检查临床早期诊断,尽早终止妊娠及支持对症治疗有望提高妊娠急性脂肪肝的母儿生存率。
Objective To investigate the diagnosis and treatment of acute fatty liver in pregnancy. Methods Retrospective analysis of 2 cases of acute fatty liver in our hospital clinical manifestations, laboratory tests, pregnancy outcomes and combined with the literature reports in recent years to summarize. Results All patients presented with anorexia, bloating, edema, jaundice and DIC during the third trimester of pregnancy. Ultrasound was “bright liver ” performance. CT showed attenuation of hepatic parenchyma. Conclusion According to the clinical manifestations and laboratory diagnosis of early diagnosis of fatty liver in pregnancy, early termination of pregnancy and supportive symptomatic treatment is expected to improve maternal and child survival in patients with acute fatty liver of pregnancy.