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目的探讨地屈孕酮治疗早期先兆流产保胎患者的临床效果。方法收集2011年6月至2014年6月收治入院的240例先兆流产患者资料,将患者采用随机数字表法分为两组,各120例,观察组患者采用地屈孕酮治疗,对照组患者采用黄体酮治疗,比较两组患者保胎成功率、平均治疗时间和不良反应。结果观察组患者保胎成功率、平均治疗时间与对照组比较,差异无统计学意义(P>0.05);观察组未出现明显不良反应,对照组有8例患者出现注射部位疼痛、硬结,局部热敷后好转。结论地屈孕酮和黄体酮作用相似,但地屈孕酮无明显不良反应,可有效提高患者的治疗依从性和耐受性。
Objective To investigate the clinical effect of dydrogesterone in the treatment of early threatened abortion miscarriage patients. Methods The data of 240 patients with threatened abortion admitted to hospital from June 2011 to June 2014 were collected. The patients were divided into two groups (120 cases each) by random number table. The patients in the observation group were treated with dydrogesterone. The patients in the control group Progesterone treatment was used to compare the success rate of miscarriage, mean treatment time and adverse reactions in both groups. Results There was no significant difference between the observation group and the control group (P> 0.05). There were no significant adverse reactions in the observation group and 8 patients in the control group had pain, induration and induration at the injection site After the heat is improved. Conclusion Dydrogesterone and progesterone have similar effects, but dydrogesterone has no obvious adverse reactions, which can effectively improve the treatment compliance and tolerability of patients.