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目的 研制一种口腔含化的具有冷敷降温、清热解毒、活血化瘀、消肿止痛、止血作用的中药冰块。方法 筛选中药组成合理配方, 并煎煮成药液, 制成冰块应用于临床, 对病人的口腔温度、疼痛、肿胀及饮食情况、伤口愈合、不良反应等指标进行了观察对比及统计学处理。结果 口腔药冰具有降低口腔温度、减轻局部肿胀及疼痛、改善病人进食的作用, 且无明显的毒副作用。结论 口腔药冰是一种将药物的药理作用与剂型的物理作用合二为一, 具有多种临床治疗作用的新剂型的中药
OBJECTIVE To develop a Chinese-made ice cube with cold-contained cooling, heat-clearing and detoxifying, promoting blood circulation and removing blood stasis, swelling, relieving pain and hemostasis. Methods The traditional Chinese medicine was screened for reasonable formula, and then decocted into liquid medicine to make ice cubes for clinical use. Oral temperature, pain, swelling, diet, wound healing and adverse reactions were observed and compared statistically . Results Oral drug ice has the effect of reducing oral temperature, relieving local swelling and pain, improving patient’s eating, and has no obvious side effects. Conclusion oral drug ice is a combination of the pharmacological effects of drugs and the physical effects of dosage forms, with a variety of clinical treatment of new formulations of traditional Chinese medicine