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利用体内荷腹水瘤模型 ,采用中性红吞噬法、染料释放法、Griess法和放射性释放法研究白桦树皮提取物 ( Extraction of Betula Platyphylla,EBP)在体内抗腹水型 S1 80和艾氏腹水癌以及对腹腔巨噬细胞功能的影响 .结果表明 ,EBP可明显延长荷腹水型 S1 80和艾氏腹水癌小鼠的生存期 ;巨噬细胞吞噬功能及分泌肿瘤坏死因子 ( TNF)和一氧化氮的功能明显增强 ,其细胞毒活性亦明显增加 ( p<0 .0 5)
Using an in vivo ascites tumor model, Neutral Red Phagocytosis, Dye-Release, Griess and Radio-Release were used to study the extraction of Betula Platyphylla (EBP) in vivo against ascites S1 80 and Ehrlich ascites carcinoma. And the effect on the function of peritoneal macrophages. The results showed that EBP can significantly prolong the survival of mice with ascites type S1 80 and Ehrlich ascites carcinoma; macrophage phagocytosis and secretion of tumor necrosis factor (TNF) and nitric oxide The function of the drug was significantly enhanced and its cytotoxic activity was also significantly increased (p<0.05).