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目的探讨肺炎支原体快速培养法与被动凝集法在小儿肺炎支原体肺炎不同病程中的应用价值。方法肺炎患儿114例,在病程5 d内分别进行肺炎支原体快速培养法及被动凝集法检测。根据临床诊断分为肺炎支原体肺炎组(A组,54例)、非肺炎支原体肺炎组(B组,60例);A组患儿在病程7~10 d用两种方法复查,比较两种检测方法的阳性率。结果 114例中,病程5 d内的肺炎支原体快速培养法与被动凝集法阳性率分别为42.1%和23.7%(P<0.05),灵敏度为83.33%和50.0%,特异度为95.0%和100%,ROC曲线下面积为89.2%和75.0%。A组病程7~10 d复查,肺炎支原体快速培养阳性35例(64.81%),被动凝集法检测支原体抗体阳性54例(100.0%)(P<0.05)。结论 合理选择检测时机,肺炎支原体快速培养法与被动凝集法对小儿肺炎支原体肺炎的临床诊断具有重要意义。
Objective To investigate the value of rapid culture of Mycoplasma pneumoniae and passive agglutination in different stages of Mycoplasma pneumoniae pneumonia in children. Methods A total of 114 children with pneumonia were enrolled in this study. Mycoplasma pneumoniae rapid culture and passive agglutination test were performed within 5 days. According to the clinical diagnosis, they were divided into Mycoplasma pneumoniae pneumonia group (A group, 54 cases) and non-Mycoplasma pneumoniae pneumonia group (B group, 60 cases) .A group of children in the course of 7 ~ 10d review by two methods, The positive rate of the method. Results Among the 114 cases, the positive rates of Mycoplasma pneumoniae rapid culture and passive agglutination were 42.1% and 23.7% (P <0.05), the sensitivity was 83.33% and 50.0%, the specificity was 95.0% and 100% , The area under the ROC curve was 89.2% and 75.0%. A group of disease course 7 ~ 10d review, rapid culture of Mycoplasma pneumoniae positive in 35 cases (64.81%), passive agglutination test mycoplasma antibody positive in 54 cases (100.0%) (P <0.05). Conclusion The reasonable choice of timing of detection, rapid culture of Mycoplasma pneumoniae and passive agglutination in children with Mycoplasma pneumoniae pneumonia clinical diagnosis is of great significance.