论文部分内容阅读
目的 探讨早期乳腺癌保乳治疗的原则和方法。方法 回顾性分析湖南省肿瘤医院 1992年 1月～ 2 0 0 2年 4月接受了保乳治疗的 3 1例早期乳腺癌资料。其中 14例肿瘤扩大切除加腋淋巴结清扫 ,5例肿瘤扩大切除 ,11例肿瘤切除 ,1例未手术。术后 17例进行了放疗和化疗 ,8例只做了放疗 ,3例只做了化疗 ,3例放化疗均未做。结果 存活时间最长 12 2个月 ,最短 6个月 ,平均3 2± 5个月 ,中位生存时间 2 2个月。 1例术后拒绝化疗第 3年死于远处转移 ,余 3 0例目前均存活 ,其中 10例已存活 3年以上 ;1例术后未放化疗者第 5年局部复发 ;保留乳房外观满意率为 93 5 %。结论 早期乳腺癌的保乳治疗应在肿瘤扩大切除加腋淋巴结清扫手术后与放疗和化疗合理的配合 ,才可能达到预期的效果
Objective To explore the principles and methods of breast-conserving treatment in early breast cancer. Methods The data of 31 cases of early breast cancer who underwent breast conserving treatment in Hunan Cancer Hospital from January 1992 to April 2002 were retrospectively analyzed. Among them, 14 patients underwent expansive resection combined with axillary lymph node dissection, 5 patients underwent tumor expansion and resection, 11 patients underwent tumor resection and 1 patient had no surgery. Radiotherapy and chemotherapy were performed in 17 cases after radiotherapy, radiotherapy was performed in 8 cases, chemotherapy was performed in 3 cases, and radiotherapy and chemotherapy were not performed in 3 cases. Results The longest survival time of 122 months, the shortest 6 months, an average of 32 ± 5 months, the median survival time of 22 months. One patient died of distant metastasis in the third year after chemotherapy. The remaining 30 patients survived at present, of whom 10 had survived for more than 3 years. One patient had local recurrence 5 years after radiotherapy and chemotherapy. The breast appearance was satisfactory Rate of 93 5%. Conclusion Breast-conserving treatment of early breast cancer should be combined with radiotherapy and chemotherapy after tumor expansion and resection and axillary lymph node dissection, so as to achieve the expected effect