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细胞因子是由炎症细胞产生和分泌的与细胞有关的蛋白质。IL-1、IL-6、TNF-α、IFN-γ、D因子等与癌症诱导的恶病质有关,这些细胞因子的传递可能是通过循环系统来完成的。老化具有进行性的糖皮质激素和儿茶酚胺浓度增加以及生长激素性激素减少的特征,这些变化导致炎症细胞因子升高,而这些细胞因子对代谢具有重要的作用。与恶病质有关的细胞因子:①肿瘤坏死因子(TNF-α):当Rouzer和Cerami等给带有寄生锥虫brucei的兔子注射TNF-α时发现,兔子在几周内发展成严重的恶
Cytokines are cell-related proteins produced and secreted by inflammatory cells. IL-1, IL-6, TNF-α, IFN-γ, D-factor, etc., are associated with cancer-induced cachexia. The delivery of these cytokines may be through the circulatory system. Aging is characterized by progressive increases in glucocorticoid and catecholamine concentrations and decreases in growth hormone hormones that result in elevated inflammatory cytokines that are important for metabolism. Cytokines related to cachexia: ① Tumor necrosis factor (TNF-α): When Rouzer and Cerami et al injected TNF-α to rabbits with brucei parasite, they found that rabbits developed severe evil within a few weeks