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目的:探讨自拟通络汤治疗急性脑梗塞患者肢体偏瘫临床疗效。方法:选用我院2012年1月-2013年1月内二科及针灸科收治患者102例(男65例,女37例),按照随机、单盲、对照原则分观察组和对照组,各51例。对照组按照常规降低颅内压、控制脑水肿、抗血小板聚集、营养脑细胞等治疗,观察组在对照组基础上加自拟活血通络方(天麻、钩藤、黄芪、全蝎、蜈蚣、地龙、桃仁、红花、赤芍、川芎、石菖蒲等组成)治疗4个疗程28d,观察患者疗效、神经功能缺损评分(NIHSS)对比变化。结果:①两组患者NIHSS评分对比,治疗后组间各时间点、数据差别有统计学意义,两组间差异有统计学意义(P<0.05)。②服药期间,治疗效果观察组明显优于对照组,有统计学意义(P<0.05)。结论:①观察组与对照组对急性脑梗塞均有一定的治疗效果。②自拟通络汤可能通过中医活血化瘀通络法,提高NIHSS评分,对急性脑梗塞偏瘫有较好的疗效。
Objective: To investigate the curative effect of self-made Tongluo Decoction on hemiplegia in patients with acute cerebral infarction. Methods: A total of 102 patients (65 males and 37 females) were enrolled in our department from January 2012 to January 2013 and were divided into observation group and control group according to randomized, single-blind and control principles 51 cases. In the control group, intracranial pressure was decreased, brain edema was controlled, antiplatelet aggregation and nutrition brain cells were treated according to the routine. The observation group was treated with Huoxuetongluo Formula (Gastrodia elata Blumee, Uncaria, Astragalus, Scorpio, Centipede, Earthworm, peach kernel, safflower, red peony root, rhizoma chuanxiong and shichangpu for 4 days for 28 days. The curative effect and neurological deficit score (NIHSS) of the patients were observed and compared. Results: ①Comparison of NIHSS scores between the two groups showed that there was a significant difference between the two groups in the time points after treatment, the difference was statistically significant (P <0.05). During medication, the treatment effect observation group was significantly better than the control group, with statistical significance (P <0.05). Conclusion: ① The observation group and the control group have certain therapeutic effect on acute cerebral infarction. ② self Tonglintang may be through the traditional Chinese medicine blood circulation method, improve NIHSS score, hemiplegia acute cerebral infarction have a good effect.