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目的探索食管癌、贲门癌、贲门失弛缓症术后胸腔感染的有效处理方法。方法选取我院胸外科2012年1月至2014年6月间因食管癌、贲门癌、贲门失弛缓症手术并发食管胸腔瘘的患者42例,分为常规+臭氧治疗组和常规治疗组。常规治疗组28例,男22例、女6例,年龄54~78(63.5±6.8)岁,行胸腔闭式引流、抗感染、营养支持治疗;常规+臭氧治疗组14例,男11例、女3例,年龄39~74(64.7±9.1)岁,行常规治疗+臭氧胸腔保留灌注治疗。结果两组年龄、性别、体重差异均无统计学意义(P>0.05),常规+臭氧治疗组疗效明显优于常规治疗组:住院时间更短(P=0.017),住院费用更低(P=0.016),死亡率[0.00%(0/14)vs.10.71%(3/28)]更低。结论臭氧具有便捷、杀菌、消毒、不良反应以及促进脓腔吸收的作用,可以提高治疗效果,缩短住院时间,减少住院费用,值得临床推广和运用。
Objective To explore the effective treatment of postoperative thoracic infection of esophageal cancer, cardiac cancer and achalasia. Methods Forty-two patients with esophageal cancer, cardiac cancer and achalasia complicated with esophageal and abdominal fistula were selected from January 2012 to June 2014 in our hospital from January 2012 to June 2014, and divided into routine + ozone treatment group and conventional treatment group. The routine treatment group consisted of 28 patients, 22 males and 6 females, aged 54-78 years old (63.5 ± 6.8) years old, with thoracic closed drainage, anti-infective and nutritional support treatment. In the routine + ozone treatment group, 14 cases were male and 11 were male, Female 3 cases, aged 39-74 (64.7 ± 9.1) years old, routine treatment + ozone chest infusion therapy. Results There was no significant difference in age, sex and weight between the two groups (P> 0.05). The curative effect of routine + ozone treatment group was significantly better than that of conventional treatment group: shorter hospital stay (P = 0.017) and lower hospitalization expense (P = 0.016), mortality [0.00% (0/14) vs.10.71% (3/28)]. Conclusion Ozone has the effect of convenience, sterilization, disinfection, adverse reactions and promotion of abscess absorption, which can improve the curative effect, shorten the length of hospital stay and reduce the cost of hospitalization. It is worth to be popularized and applied clinically.