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目的:观察应用双岐杆菌四联活菌片预防毛细支气管炎继发腹泻的疗效。方法:将毛细支气管炎患儿123例,随机分为预防组67例和对照组56例。对照组给予常规治疗,预防组在常规治疗基础上加用双岐杆菌四联活菌片口服6,个月内2次/d,0.5 g/次;6个月以上2次/d,1 g/次,疗程7 d。结果:预防组21例发生继发性腹泻,发生率为31.3%(21/67),对照组29例发生继发性腹泻,发生率为51.8%(29/56),两组比较差异有统计学意义(P<0.05);预防组1例发生重型腹泻,发生率为1.5%(1/67),对照组7例发生重型腹泻,发生率为12.5%(7/56),两组比较差异有统计学意义(P<0.05)。结论:毛细支气管炎患儿服用双岐杆菌四联活菌片可使继发性腹泻发生率降低。
Objective: To observe the application of Bifidobacterium quadriceps could prevent the secondary diarrhea caused by bronchiolitis. Methods: 123 children with bronchiolitis were randomly divided into prevention group (67 cases) and control group (56 cases). The control group was given conventional treatment. The prevention group was given oral administration of Bifidobacterium quadricepsicum via oral administration routinely on the basis of routine treatment for 6 times in 2 months / d and 0.5 g / time in 6 months and 2 g / / Times, treatment 7 d. Results: Secondary diarrhea was found in 21 cases of prevention group (31.3%, 21/67), secondary diarrhea occurred in 29 cases of control group (51.8%, 29/56), with statistical difference (P <0.05). In the prevention group, one case had severe diarrhea, the incidence rate was 1.5% (1/67), in the control group, 7 cases had severe diarrhea, the incidence rate was 12.5% (7/56). There was significant difference between the two groups There was statistical significance (P <0.05). Conclusions: The incidence of secondary diarrhea is reduced in children with bronchiolitis treated with live tetanus Bifidobacterium.