从γ-丁酸内酯出发,制得3-(3-羟基丙基)-4-氨基-5-巯基-1,2,4-三唑,它与4-甲氧基溴代苯乙酮反应,合成了3-(羟基丙基)-6-(4-甲氧基苯基)-7H-1,2,4并[3,4-b]-1,3,4-噻二嗪氢溴酸盐,通过元素分析、红外光谱、碳谱、氢谱进行表征,并利用单晶X-射线衍射法测定其结构.这是首次报道的三唑并噻二嗪类稠杂环化合物氢溴酸盐,晶体属单斜晶系,C2/c空间群,a=2.3101(17)nm,b=0.7207(5)nm,c=2.0201(16)nm,β=112.875(8)°,Z=8,F(000)=1552,R1=0.0472. Starting from γ-butyrolactone, 3- (3-hydroxypropyl) -4-amino-5-mercapto-1,2,4-triazole was obtained which was reacted with 4-methoxybromoacetophenone The reaction of 3- (hydroxypropyl) -6- (4-methoxyphenyl) -7H-1,2,4-and [3,4-b] -1,3,4-thiadiazine hydrogen The bromate was characterized by elemental analysis, infrared spectrum, carbon spectrum and hydrogen spectrum, and its structure was determined by single crystal X-ray diffraction. This is the first report of the triazole and thiadiazole fused heterocyclic compound hydrobromide A = 2.3101 (17) nm, b = 0.7207 (5) nm, c = 2.0201 (16) nm, β = 112.875 (8) ° and Z = 8, F (000) = 1552, R1 = 0.0472.