母婴同室新生儿黄疸的早期干预及茵栀黄颗粒联合益生菌治疗的临床观察

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目的观察母婴同室新生儿黄疸的早期干预及茵栀黄颗粒联合益生菌治疗新生儿高胆红素血症的临床效果,提高母婴同室中新生儿黄疸的诊断及处理水平。方法选取近6个月本院产科母婴同室且1周内出现不同程度黄疸的新生儿246例,随机分为对照组及干预组各123例,对照组给予常规护理,干预组在常规护理基础上给予抚触按摩、促进排便、游泳运动等干预措施,其中经皮胆红素≥221umol/L(12.9mg/dl)的新生儿35例,对这35例新生儿均加用茵栀黄颗粒联合益生菌(枯草杆菌二联活菌颗粒)冲服,观察患儿7 d内黄疸的变化,分析新生儿黄疸的病因、诊断及处理方法。结果出现黄疸的所有新生儿经过干预措施后7 d内黄疸指数下降显著优于对照组。35例新生儿高胆红素血症患儿均获及时诊断,其中30例黄疸明显下降,无并发症发生。余5例黄疸较重患儿转入新生儿病房治疗。分析母婴同室新生儿出现黄疸原因,妊娠合并症的母亲占33.33%,母婴ABO血型不合占24.78%,宫内缺氧占14.63%,头颅血肿占11.38%,纯母乳喂养占7.72%,喂养不足占6.91%,余1.22%未查明原因。结论母婴同室中的新生儿经专职儿科医生的早期干预和及时诊治后体内胆红素水平下降,大多数病理性黄疸患儿可以在产科母婴同室治疗好转。 Objective To observe the early intervention of maternal and neonatal jaundice with neonatal jaundice and Yinzhihuang granule combined with probiotics in the treatment of neonatal hyperbilirubinemia clinical efficacy and improve the diagnosis and treatment of neonatal jaundice in the same room. Methods A total of 246 neonates with maternity and maternity in our hospital during the past 6 months and different degrees of jaundice within 1 week were randomly divided into control group and 123 cases in the intervention group. The control group was given routine nursing. The intervention group received routine nursing On the massage, to promote defecation, swimming and other interventions, including transcutaneous bilirubin ≥ 221umol / L (12.9mg / dl) in 35 newborns, 35 newborns were added Yinzhihuang granules Joint probiotics (Bacillus subtilis bivalent live particles) Chongfu, observed in children with jaundice within 7 days of change, analysis of the etiology, diagnosis and treatment of neonatal jaundice. Results All neonates with jaundice had a significantly lower jaundice index within 7 days after intervention, which was significantly better than that of the control group. Thirty-five neonates with hyperbilirubinaemia were diagnosed in time, of which 30 cases of jaundice decreased significantly and no complication occurred. More than 5 cases of jaundice heavier children into neonatal ward treatment. Analysis of neonatal maternal and neonatal jaundice causes, pregnancy complications accounted for 33.33% of mothers, maternal and child ABO blood group accounted for 24.78%, intrauterine hypoxia 14.63%, head hematoma 11.38%, exclusive breastfeeding 7.72%, feeding Less than 6.91%, 1.22% did not identify the reasons. Conclusion Neonates in maternal and infant room with early intervention by full-time pediatricians and the timely diagnosis and treatment of bilirubin levels decreased, the majority of children with pathological jaundice can be improved in the maternity room maternity.
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