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半乳糖凝集素-3(Galectin-3,Gal-3)是近年来发现的一种新型生物标记物,介导组织的炎症和纤维化。目前已证实Gal-3在心力衰竭(心衰)心室重构中有促进炎症和促纤维化作用,Gal-3可能为心衰的诊断及治疗提供新的依据。
Galectin-3 (Gal-3) is a new type of biomarker discovered in recent years, which mediates the inflammation and fibrosis of tissues. Gal-3 has been shown to promote inflammation and promote fibrosis in heart failure (heart failure) ventricular remodeling, Gal-3 may provide a new basis for the diagnosis and treatment of heart failure.