一、雌激素的分子生物学早知雌激素对特定组织的生化生理过程起着一种调节、修饰的作用,而对另一些组织不产生明显的影响。1962年已有人提出在某些能保留雌激素而称之为靶组织的细胞中存在着一种能专一地结合雌二醇的分子。稍后就发现大鼠子宫的胞浆组份中的确存在着一种称为雌二醇受体的大分子。其后又发现 First, the molecular biology of estrogen Early known estrogen on the specific biochemical physiological processes play a role in regulation, modification, while other organizations do not have a significant impact. It has been suggested in 1962 that in certain cells that retain estrogen, the so-called target tissue, there is a molecule that specifically binds to estradiol. It was later discovered that there was indeed a large molecule called the estradiol receptor in the cytoplasmic fraction of the rat uterus. Then discovered again