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目的分析广州口岸近年输入性登革热病例的流行病学情况,为国内登革热疫情的溯源和制定有效的预防控制措施提供依据。方法对2009-2015年经广州口岸入境、疑似登革热病例进行流行病学调查和登革病毒的实验室核酸检测,用描述性流行病学方法分析其流行特征和流行因素。结果 2009-2015年,使用实时荧光RT-PCR共检出输入性登革热病例152例,近3年输入病例逐步升高。89.5%病例来自亚洲,其中东南亚占87.5%,主要来源于泰国、越南、马来西亚、印度尼西亚、缅甸和新加坡等地。输入性登革热病例主要集中在21~40岁,男性占77%。全年均有输入性病例报告,其中第三季度和第四季度是高峰期,10月份输入性病例最多。结论东南亚地区的入境人员已成为广东省输入性登革热病例的重点人群。广东口岸地区面临输入性登革热的威胁,出入境检验检疫机构应及时掌握国内外疫情信息,加强口岸检疫查验、疾病监测,一旦发现疫情,及时采取有效的控制措施,防止输入性登革热造成本地疫情的爆发。
Objective To analyze the epidemiology of imported dengue cases in Guangzhou Port in recent years and provide evidence for the traceability of dengue fever in the country and to formulate effective prevention and control measures. Methods Epidemiological investigation and laboratory nucleic acid detection of dengue virus from 2009 to 2015 in Guangzhou port were conducted, and the epidemiological and epidemiological factors were analyzed by descriptive epidemiology. Results In 2009-2015, 152 cases of imported dengue were detected by real-time fluorescence RT-PCR. The cases of imported dengue increased gradually in the recent 3 years. 89.5% of the cases came from Asia, of which 87.5% were from Southeast Asia, mainly from Thailand, Vietnam, Malaysia, Indonesia, Myanmar and Singapore. The incidence of imported dengue cases mainly concentrated in 21 to 40 years old, men accounted for 77%. Input cases were reported throughout the year, with the third quarter and the fourth quarter being the peak, with the largest number of imported cases in October. Conclusion Inbound personnel in Southeast Asia have become the key population of imported dengue cases in Guangdong Province. Guangdong ports are facing the threat of imported dengue. Entry-exit inspection and quarantine agencies should keep abreast of epidemic situation information at home and abroad, strengthen quarantine inspection and disease surveillance at ports. Once an outbreak has been found, effective control measures should be taken in time to prevent local epidemics caused by imported dengue break out.