环孢素A(CyA)在预防/治疗移植排斥反应中有效,这主要归因于它能抑制活化T淋巴细胞产生细胞因子而起到免疫抑制作用。CyA在数种自身免疫和炎症性疾病中也有效,表明它也具有抗炎作用。作者已证实,在体外CyA在其药理学浓度(8nM～800nM)下能10％～ Cyclosporine A (CyA) is effective in the prevention / treatment of transplant rejection mainly due to its immunosuppressive effects by inhibiting the production of cytokines by activated T lymphocytes. CyA is also effective in several autoimmune and inflammatory diseases, indicating that it also has an anti-inflammatory effect. The authors have demonstrated that in vitro CyA at its pharmacological concentration (8nM ~ 800nM) can 10% ~