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目的研究有机锡化合物急性中毒的临床特点与治疗方法。方法回顾性分析51例有机锡化合物急性中毒患者的临床表现和治疗措施。结果51例有机锡化合物急性中毒患者的主要症状是头晕(33人)、头痛(18人)、疲乏(34人)、失眠(7人)、记忆减退(11人),恶心、呕吐(7人)等;主要体征是心率减慢(26人),腹壁反射轻度减弱(12人)等;辅助检查示所有患者均出现低血钾,46人伴低血钙,44人伴心电图异常。结论有机锡化合物急性中毒以神经精神症状和低血钾症为临床的主要表现;治疗原则以对症、支持治疗为主。
Objective To study the clinical characteristics and treatment of acute poisoning of organotin compounds. Methods Retrospective analysis of 51 cases of organotin compounds acute poisoning clinical manifestations and treatment measures. Results The main symptoms of 51 patients with acute poisoning of organotin compounds were dizziness (33), headache (18), fatigue (34), insomnia (7), memory loss (11), nausea and vomiting ); The main signs are slow heart rate (26), mild abdominal wall reflex (12), etc .; assisted examination showed that all patients were hypokalemia, 46 were with hypocalcemia, 44 were with ECG abnormalities. Conclusion Acute poisoning of organotin compounds is the main clinical manifestations of neuropsychiatric symptoms and hypokalemia. The treatment principle is symptomatic and supportive therapy.